Never heard of MBone, thanks for sharing. I think the fact that there is currently basically one successful video streaming service is indicative of how hard it is to run one. The bandwidth and performance it takes is huge, so unless a federated service is a paid-for service or receives huge donations there are never going to be enough resources to anywhere near match the performance of YouTube.

I’m not doubting which thing is worse, dementia is certainly worse, I just mean that we don’t know how affective the drug is against dementia.

Depends what the comparative offsets are

Increased risk of arthritic conditions sounds pretty bad…